Human PRTN3, recombinant

Human PRTN3, recombinant
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NOV-DC628.50ug 50 µg - -

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57.00€
NOV-DC628.500ug 500 µg - -

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400.00€
NOV-DC628.1mg 1 mg - -

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600.00€
 
Recombinant Human Proteinase 3/PRTN3/Myeloblastin (C-6His) is produced by Mammalian expression... more
Product information "Human PRTN3, recombinant"
Recombinant Human Proteinase 3/PRTN3/Myeloblastin (C-6His) is produced by Mammalian expression system and the target gene is expressed with a 6His tag at the C-terminus. Protein function: Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [The UniProt Consortium]
Keywords: MBN, PR3, P29, NP-4, PR-3, AGP7, PRTN3, Myeloblastin, C-ANCA antigen, Wegener autoantigen, Leukocyte proteinase 3, Neutrophil proteinase 4, Recombinant Human PRTN3
Supplier: Novoprotein
Supplier-Nr: DC628

Properties

Conjugate: No
Host: Human cells
Species reactivity: human
MW: 25.64 kD
Format: Solution

Database Information

KEGG ID : K01350 | Matching products
UniProt ID : P24158 | Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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