Human PARVA, recombinant (C-6His)

Recombinant Human Alpha-Parvin is produced by our E.coli expression system and the target gene encoding Met1-Glu372 is expressed with a 6His tag at the C-terminus. Protein function: Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development. Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishment of cell polarity, cell adhesion, cell spreading, and directed cell migration. [The UniProt Consortium]