Human MBP-GPR75 full length protein-synthetic nanodisc

Item number	Size	Manual	SDS	Delivery time	Price
DIM-FLP110031.10	10 µg	-	-	7 - 16 business days*	1,317.00€
DIM-FLP110031.50	50 µg	-	-	7 - 16 business days*	6,437.00€
DIM-FLP110031.100	100 µg	-	-	7 - 16 business days*	11,704.00€

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G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to... more

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Product information "Human MBP-GPR75 full length protein-synthetic nanodisc"

G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.. Human MBP-GPR75 full length protein-synthetic nanodisc. Protein function: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor. [The UniProt Consortium]

Keywords:	GPR75, Probable G-protein coupled receptor 75
Supplier:	DIMA
Supplier-Nr:	FLP110031

Properties

Application:	Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization
Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	99.4 kD
Format:	Lyophilized

Database Information

KEGG ID :	K08417 \| Matching products
UniProt ID :	O95800 \| Matching products
Gene ID :	GeneID 10936 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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