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Human KCNE5-Strep full length protein-synthetic nanodisc
Product information "Human KCNE5-Strep full length protein-synthetic nanodisc"
This gene encodes a member of a family of single pass transmembrane domain proteins that function as ancillary subunits to voltage-gated potassium channels. Members of this family affect diverse processes in potassium channel regulation, including ion selectivity, voltage dependence, and anterograde recycling from the plasma membrane. Variants of this gene are associated with idiopathic ventricular fibrillation and Brugada syndrome. [provided by RefSeq, Nov 2016]. Human KCNE5-Strep full length protein-synthetic nanodisc. Protein function: Potassium channel ancillary subunit that is essential for generation of some native K(+) currents by virtue of formation of heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. Functions as an inhibitory beta- subunit of the repolarizing cardiac potassium ion channel KCNQ1. [The UniProt Consortium]
Keywords:
KCNE5, AMMECR2, Potassium channel subunit beta MiRP4, AMME syndrome candidate gene 2 protein, Potassium voltage-gated channel subfamily E member 1-like protein, Potassium voltage-gated channel subfamily E regulatory beta subunit 5
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