Human IL-3 R Beta/CD131 Protein

Recombinant Human IL-3 R Beta/CD131 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Thr17-Trp443. Interleukin-3 receptor (IL-3R) is a heterodimer that comprises an IL-3 specific alpha chain (IL-3R alpha) and a common beta chain (beta C) that is shared with the receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF) and IL-5. The beta c subunit does not bind any cytokine by itself but is involved in the formation of high-affinity functional receptors for IL-5 and GM-CSF. These receptors belong to the cytokine receptor superfamily, but they are structurally and functionally more related to each other and thus make up a distinct subfamily. Protein function: High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. [The UniProt Consortium]