Human IL-15RAandIL-15 (C-Fc) Protein

Human IL-15RAandIL-15 (C-Fc) Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
DIM-PME30072.50 50 µg - -

7 - 16 business days*

527.00€
 
Recombinant Human Interleukin-15 Receptor Alpha and Interleukin-15 Fusion Protein is produced by... more
Product information "Human IL-15RAandIL-15 (C-Fc) Protein"
Recombinant Human Interleukin-15 Receptor Alpha and Interleukin-15 Fusion Protein is produced by our Mammalian expression system and the target gene encoding Ile31-Asp96andAsn49-Ser162(Asn120Asp) is expressed with a Fc tag at the C-terminus.. , Protein function: High-affinity receptor for interleukin-15 (PubMed:8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed:15123770). In neutrophils, required for IL15- induced phagocytosis in a SYK-dependent manner (PubMed:15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed:10480910). [The UniProt Consortium]
Keywords: IL15RAandIL15, Interleukin-15, IL-15, IL15, IL-15 receptor subunit alpha, IL-15RA, IL-15R-alpha, interleukin-15 receptor subunit alpha
Supplier: DIMA
Supplier-Nr: PME30072

Properties

Conjugate: No
Host: Human cells
Species reactivity: human
MW: 46.9 kD
Purity: >95% (SDS-PAGE)
Format: Lyophilized

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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