Human GLRA2-Strep full length protein-synthetic nanodisc

Item number	Size	Manual	SDS	Delivery time	Price
DIM-FLP120820.10	10 µg	-	-	7 - 16 business days*	1,185.00€
DIM-FLP120820.50	50 µg	-	-	7 - 16 business days*	5,793.00€
DIM-FLP120820.100	100 µg	-	-	7 - 16 business days*	10,534.00€

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The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The... more

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Product information "Human GLRA2-Strep full length protein-synthetic nanodisc"

The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]. Human GLRA2-Strep full length protein-synthetic nanodisc. Protein function: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488). Channel opening is also triggered by taurine and beta-alanine (PubMed:15302677). Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488). Plays a role in cellular responses to ethanol (PubMed:23895467). [The UniProt Consortium]

Keywords:	GLRA2, Glycine receptor subunit alpha-2
Supplier:	DIMA
Supplier-Nr:	FLP120820

Properties

Application:	Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization
Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	52 kD
Format:	Lyophilized

Database Information

KEGG ID :	K05194 \| Matching products
UniProt ID :	P23416 \| Matching products
Gene ID :	GeneID 2742 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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