Human CD68, recombinant (C-Fc)

Recombinant Human Macrosialin is produced by our Mammalian expression system and the target gene encoding Asn22-Ile320 is expressed with a human IgG1 Fc tag at the C-terminus. Protein function: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. [The UniProt Consortium]