Human CD58, recombinant (C-Fc)

Recombinant Human Lymphocyte Function-associated Antigen 3 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215 is expressed with a human IgG1 Fc tag at the C-terminus. Protein function: Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. [The UniProt Consortium]