Human CD58 Protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
KT-CD5-HM208-100UG	100 µg		-		7 - 10 business days*		269.00€
KT-CD5-HM208-500UG	500 µg		-		7 - 10 business days*		898.00€

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Recombinant Human CD58 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It... more

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Product information "Human CD58 Protein"

Recombinant Human CD58 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe29-Arg215. Loss of CD58 is a common mechanism for tumor immune evasion in lymphoid malignancies. CD58 loss is known to occur due to both genetic and non-genetic causes, therefore, we hypothesized that restoring CD58 expression in lymphoma cells may be an effective treatment approach. EZH2 is involved in the epigenetic silencing of CD58 in lymphoma cells as a mechanism for tumor immune escape, and EZH2 inhibitors are able to restore epigenetically suppressed CD58 expression.

Keywords:	Lymphocyte function-associated antigen 3,Ag3,CD58,LFA3
Supplier:	KACTUS
Supplier-Nr:	CD5-HM208

Properties

Host:	Human cells
Species reactivity:	human
MW:	48.1 kD
Purity:	>95% (Tris-Bis PAGE),>95% (HPLC)
Format:	Lyophilized

Database Information

UniProt ID :

Q9BRW0 | Matching products

Handling & Safety

Storage:	-80°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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