Human CD316, recombinant (C-Fc)

Recombinant Human Immunoglobulin Superfamily Member 8 is produced by our Mammalian expression system and the target gene encoding Arg28-Thr579 is expressed with a human IgG1 Fc tag at the C-terminus. Protein function: May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. [The UniProt Consortium]