Human BACD1-Strep full length protein-synthetic nanodisc

Item number	Size	Manual	SDS	Delivery time	Price
DIM-FLP120718.10	10 µg	-	-	7 - 16 business days*	1,162.00€
DIM-FLP120718.50	50 µg	-	-	7 - 16 business days*	5,680.00€
DIM-FLP120718.100	100 µg	-	-	7 - 16 business days*	10,327.00€

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Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required... more

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Product information "Human BACD1-Strep full length protein-synthetic nanodisc"

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission (By similarity).[UniProtKB/Swiss-Prot Function]. Human BACD1-Strep full length protein-synthetic nanodisc. Protein function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission. [The UniProt Consortium]

Keywords:	KCTD13, FKSG86, hBACURD1, TNFAIP1-like protein, Polymerase delta-interacting protein 1, BTB/POZ domain-containing protein KCTD13, BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1
Supplier:	DIMA
Supplier-Nr:	FLP120718

Properties

Application:	Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization
Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	36.4 kD
Format:	Lyophilized

Database Information

KEGG ID :	K15074 \| Matching products
UniProt ID :	Q8WZ19 \| Matching products
Gene ID :	GeneID 253980 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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