HORMAD2 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-5225-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-5225-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Essential for synapsis surveillance during meiotic prophase via the recruitment... more

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Product information "HORMAD2 (human), recombinant protein"

Protein function: Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid- pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break- independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation. [The UniProt Consortium]

Keywords:	HORMA domain-containing protein 2, Recombinant Human HORMAD2 Protein
Supplier:	Absea
Supplier-Nr:	PP-5225-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	29 kD
Format:	Lyophilized

Database Information

KEGG ID :	K12778 \| Matching products
UniProt ID :	Q8N7B1 \| Matching products
Gene ID :	GeneID 150280 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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