HOMER3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-407-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-407-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Postsynaptic density scaffolding protein. Binds and cross- links cytoplasmic... more

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Product information "HOMER3 (human), recombinant protein"

Protein function: Postsynaptic density scaffolding protein. Binds and cross- links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER- associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway. Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA (PubMed:18218901). [The UniProt Consortium]

Keywords:	Homer protein homolog 3, Homer-3, Recombinant Human HOMER3 Protein
Supplier:	Absea
Supplier-Nr:	PP-407-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	23 kD
Format:	Lyophilized

Database Information

KEGG ID :	K15010 \| Matching products
UniProt ID :	Q9NSC5 \| Matching products
Gene ID :	GeneID 9454 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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