HOMER2 PrEST Antigen

HOMER2 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST81437.100 100 µl - -

7 - 10 business days*

247.00€
 
Protein function: Postsynaptic density scaffolding protein. Binds and cross- links cytoplasmic... more
Product information "HOMER2 PrEST Antigen"
Protein function: Postsynaptic density scaffolding protein. Binds and cross- links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER- associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (PubMed:9808459). Required for normal hearing (PubMed:25816005). Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway. Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA (PubMed:18218901). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: Homer-2, Cupidin, Homer protein homolog 2
Supplier: Atlas Antibodies
Supplier-Nr: APrEST81437

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "HOMER2 PrEST Antigen"
Write a review
or to review a product.
Viewed