HN1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-5538-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-5538-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578,... more

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Product information "HN1 (human), recombinant protein"

Protein function: Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408). [The UniProt Consortium]

Keywords:	Jupiter microtubule associated homolog 1, Androgen-regulated protein 2, Hematological and neurological expressed 1 protein) [Cleaved into: Jupiter microtubule associated homolog 1, N-terminally processed], Recombinant Human JPT1 Protein
Supplier:	Absea
Supplier-Nr:	PP-5538-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	17 kD
Format:	Lyophilized

Database Information

UniProt ID :	Q9UK76 \| Matching products
Gene ID :	GeneID 51155 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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