HLADG/CD74 Protein(C-mFc-6His) (recombinant mouse)

Protein Construction: Recombinant Mouse HLA class II histocompatibility antigen gamma chain is produced by our Mammalian expression system and the target gene encoding Gln56-Leu215 is expressed with a mFc, 6His tag at the C-terminus. Sequence: Gln56-Leu215. Fusion tag: C-mFc-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 45-55 kDa. Protein function: Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Protein function: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. [The UniProt Consortium]