HIPK3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-8844-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-8844-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Serine/threonine-protein kinase involved in transcription regulation, apoptosis... more

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Product information "HIPK3 (human), recombinant protein"

Protein function: Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2- mediated activation of the osteocalcin FGF-responsive element (OCFRE). [The UniProt Consortium]

Keywords:	Homeodomain-interacting protein kinase 3, Androgen receptor-interacting nuclear protein kinase, ANPK, Fas-interacting serine/threonine-protein kinase, FIST, Homolog of protein kinase YAK1, Recombinant Human HIPK3 Protein
Supplier:	Absea
Supplier-Nr:	PP-8844-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	20.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K08826 \| Matching products
UniProt ID :	Q9H422 \| Matching products
Gene ID :	GeneID 10114 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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