HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Price
TGM-TMPJ-00791-5ug	5 µg	-	-	-	5 - 10 business days*	68.00€
TGM-TMPJ-00791-20ug	20 µg	-	-	-	5 - 10 business days*	166.00€
TGM-TMPJ-00791-100ug	100 µg	-	-	-	5 - 10 business days*	502.00€
TGM-TMPJ-00791-200ug	200 µg	-	-	-	5 - 10 business days*	870.00€

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Description: ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF... more

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Product information "HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)"

Description: ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpression of ErbB2 has been reported associated with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate and ovarian cancers. Rat ERBB2 is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. ErbB2 mediates signalling pathways which involve mitogen-activated protein kinase and phosphatidylinositol-3 kinase, this receptor plays a key role in development, cell proliferation and differentiation.

Keywords:	p185erbB2 , Epidermal growth factor receptor-related protein , p185neu , EGFR2 , ERBB2 , CD340 , Proto-oncogene c-ErbB-2 , Proto-oncogene Neu , Receptor tyrosine-protein kinase erbB-2
Supplier:	TargetMol
Supplier-Nr:	TMPJ-00791