GUK1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-5094-L.20	20 µg		-	-	10 - 15 business days*		115.00€
ABS-PP-5094-L.100	100 µg		-	-	10 - 15 business days*		205.00€

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Protein function: Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP... more

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Product information "GUK1 (human), recombinant protein"

Protein function: Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP) (PubMed:31201273). Involved in the cGMP metabolism in photoreceptors. It may also have a role in the survival and growth progression of some tumors (PubMed:31201273). In addition to its physiological role, GUK1 is essential for convert prodrugs used for the treatment of cancers and viral infections into their pharmacologically active metabolites, most notably acyclovir, ganciclovir, and 6-thioguanine and its closely related analog 6-mercaptopurine (PubMed:197968, PubMed:6248551, PubMed:6306664). [The UniProt Consortium]

Keywords:	Guanylate kinase, GMP kinase, Guanylate kinase 1, Recombinant Human GUK1 Protein
Supplier:	Absea
Supplier-Nr:	PP-5094-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	23 kD
Format:	Lyophilized

Database Information

KEGG ID :	K00942 \| Matching products
UniProt ID :	Q16774 \| Matching products
Gene ID :	GeneID 2987 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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