GNA13 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-8830-L.20	20 µg		-	-	10 - 15 business days*		115.00€
ABS-PP-8830-L.100	100 µg		-	-	10 - 15 business days*		205.00€

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Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or... more

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Product information "GNA13 (human), recombinant protein"

Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16787920, PubMed:16705036, PubMed:27084452). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1). Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (PubMed:16787920, PubMed:16705036, PubMed:27084452). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333). [The UniProt Consortium]

Keywords:	Guanine nucleotide-binding protein subunit alpha-13, G alpha-13, G-protein subunit alpha-13, Recombinant Human GNA13 Protein
Supplier:	Absea
Supplier-Nr:	PP-8830-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	25 kD
Format:	Lyophilized

Database Information

KEGG ID :	K04639 \| Matching products
UniProt ID :	Q14344 \| Matching products
Gene ID :	GeneID 10672 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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