GMNN (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-7574-L.20	20 µg		-	-	10 - 15 business days*		115.00€
ABS-PP-7574-L.100	100 µg		-	-	10 - 15 business days*		205.00€

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Protein function: Inhibits DNA replication by preventing the incorporation of MCM complex into... more

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Product information "GMNN (human), recombinant protein"

Protein function: Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC) (PubMed:9635433, PubMed:14993212, PubMed:20129055, PubMed:24064211). It is degraded during the mitotic phase of the cell cycle (PubMed:9635433, PubMed:14993212, PubMed:24064211). Its destruction at the metaphase- anaphase transition permits replication in the succeeding cell cycle (PubMed:9635433, PubMed:14993212, PubMed:24064211). Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing (PubMed:20129055). Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control (PubMed:22615398). [The UniProt Consortium]

Keywords:	Geminin, Recombinant Human GMNN Protein
Supplier:	Absea
Supplier-Nr:	PP-7574-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	21.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K10749 \| Matching products
UniProt ID :	O75496 \| Matching products
Gene ID :	GeneID 51053 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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