FRMD8 PrEST Antigen

FRMD8 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST86402.100 100 µl - -

3 - 8 business days*

264.00€
 
Protein function: Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and... more
Product information "FRMD8 PrEST Antigen"
Protein function: Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cell surface (PubMed:29897333, PubMed:29897336). Negatively regulates Wnt signaling, possibly by antagonizing the recruitment of AXIN1 to LRP6 (PubMed:19572019). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: iTAP, Bili, FRMD8, FKSG44, iRhom tail-associated protein, Band4.1 inhibitor LRP interactor, FERM domain-containing protein 8
Supplier: Atlas Antibodies
Supplier-Nr: APrEST86402

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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