FRMD8 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6818-L.20	20 µg		-	-	10 - 15 business days*		115.00€
ABS-PP-6818-L.100	100 µg		-	-	10 - 15 business days*		205.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and... more

Close menu

Product information "FRMD8 (human), recombinant protein"

Protein function: Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cell surface (PubMed:29897333, PubMed:29897336). Negatively regulates Wnt signaling, possibly by antagonizing the recruitment of AXIN1 to LRP6 (PubMed:19572019). [The UniProt Consortium]

Keywords:	FERM domain-containing protein 8, Band4.1 inhibitor LRP interactor, Bili, iRhom tail-associated protein, iTAP, Recombinant Human FRMD8 Protein
Supplier:	Absea
Supplier-Nr:	PP-6818-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	10.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K23972 \| Matching products
UniProt ID :	Q9BZ67 \| Matching products
Gene ID :	GeneID 83786 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

Information about the product reference will follow. more

Close menu

You will get a certificate here

Go back

Read, write and discuss reviews... more

Close menu

Customer review for "FRMD8 (human), recombinant protein"

Write a review