FAS (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PQ-385-L.20	20 µg		-	-	10 - 15 business days*		295.00€
ABS-PQ-385-L.100	100 µg		-	-	10 - 15 business days*		565.00€

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Protein function: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the... more

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Product information "FAS (human), recombinant protein"

Protein function: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). [The UniProt Consortium]

Keywords:	Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD antigen CD95, Recombinant Human FAS Protein
Supplier:	Absea
Supplier-Nr:	PQ-385-L

Properties

Conjugate:	No
Host:	human cells
Species reactivity:	human
MW:	12.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K04390 \| Matching products
UniProt ID :	P25445 \| Matching products
Gene ID :	GeneID 355 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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