FABP4 (human, recombinant)

FABP4 (human, recombinant)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10009549-100 100 µg -

6 - 10 business days*

472.00€
 
Fatty acid binding protein 4 (FABP4) is a member of the intracellular lipid-binding protein... more
Product information "FABP4 (human, recombinant)"
Fatty acid binding protein 4 (FABP4) is a member of the intracellular lipid-binding protein (iLBP) family. It is composed of a beta-barrel, which forms the lipid-binding site, and two alpha-helices that form a lid on the beta-barrel. FABP4 is primarily expressed in adipocytes but has also been found in activated macrophages. It is involved in lipid transport and metabolism, insulin resistance, and angiogenesis, and its expression is induced by long-chain fatty acids and peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. Knockout of Fabp4 prevents the development of atherosclerosis in ApoE-/- mice and increases body weight gain and insulin sensitivity in ob/ob mice. Serum levels of FABP4 are increased in patients with colorectal cancer, and serum and synovial fluid levels of FABP4 are increased in patients with rheumatoid arthritis. Cayman's FABP4 (human, recombinant) protein can be used for lipid-binding assays and Western blot (WB) applications.Synonyms: Adipocyte FABP, A-FABP, ALBP, aP2, Fatty Acid Binding Protein 4, Fatty Acid Binding Proetein (Adipocyte). Purity: >90% estimated by SDS-PAGE. Source: Active N-terminal His-tagged recombinant human FABP4 expressed in E. coli. Amino Acids: 1-132 (full length). MW: 18.8 kDa. Formulation: (Request formulation change), 50 mM of sodium phosphate, pH 7.2, with 100 mM sodium chloride and 20% glycerol. UniProt Accession #: P15090.
Keywords: ALBP, ALBP, FABP4, AFABP, AFABP, A-FABP, A-FABP, Fatty acid-binding protein 4, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, Adipocyte lipid-binding protein, Fatty acid-binding protein, adipocyte, Fatty acid-binding protein, adipocyte, Ad
Supplier: Cayman Chemical
Supplier-Nr: 10009549

Properties

Application: WB
Conjugate: No
MW: 18,8 kD
Purity: >90% estimated by SDS-PAGE
Format: Solution

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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