Envelope glycoprotein C (gC), recombinant human herpesvirus 2

Organism: Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2). Source: in vitro E.coli expression system. Expression Region: 28-480aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: SPGRTITVGP RGNASNAAPS ASPRNASAPR TTPTPPQPRK ATKSKASTAK PAPPPKTGPP KTSSEPVRCN RHDPLARYGS RVQIRCRFPN STRTEFRLQI WRYATATDAE IGTAPSLEEV MVNVSAPPGG QLVYDSAPNR TDPHVIWAEG AGPGASPRLY SVVGPLGRQR LIIEELTLET QGMYYWVWGR TDRPSAYGTW VRVRVFRPPS LTIHPHAVLE GQPFKATCTA ATYYPGNRAE FVWFEDGRRV FDPAQIHTQT QENPDGFSTV STVTSAAVGG QGPPRTFTCQ LTWHRDSVSF SRRNASGTAS VLPRPTITME FTGDHAVCTA GCVPEGVTFA WFLGDDSSPA EKVAVASQTS CGRPGTATIR STLPVSYEQT EYICRLAGYP DGIPVLEHHG SHQPPPRDPT ERQVIRAVEG AGIGVAVLVA VVLAGTAVVY LTHASSVRYR RLR. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. Relevance: Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate . Also plays a role in host immune evasion by inhibiting the host complement cascade activation. Reference: "Complement component C3b binds directly to purified glycoprotein C of herpes simplex virus types 1 and 2." Eisenberg R.J., Ponce de Leon M., Friedman H.M., Fries L.F., Frank M.M., Hastings J.C., Cohen G.H. Microb. Pathog. 3:423-435(1987). Function: nan