DRG1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-8662.20	20 µg	-	-	-	Request delivery time estimate		90.00€
ABS-PP-8662.100	100 µg	-	-	-	Request delivery time estimate		180.00€

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Protein function: Catalyzes the conversion of GTP to GDP through hydrolysis of the... more

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Product information "DRG1 (human), recombinant protein"

Protein function: Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP (PubMed:29915238, PubMed:23711155). Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions (PubMed:23711155). When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation (PubMed:19819225, PubMed:29915238). Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions (PubMed:28855639). [The UniProt Consortium]

Keywords:	Developmentally-regulated GTP-binding protein 1, DRG-1, Neural precursor cell expressed developmentally down-regulated protein 3, NEDD-3, Translation factor GTPase DRG1, TRAFAC GTPase DRG1, Recombinant Human DRG1 Protein
Supplier:	Absea
Supplier-Nr:	PP-8662

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	38 kD
Format:	Solution

Database Information

UniProt ID :	Q9Y295 \| Matching products
Gene ID :	GeneID 4733 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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