DOCK8 Protein, Mouse, Recombinant (E. coli, His)

DOCK8 Protein, Mouse, Recombinant (E. coli, His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-TMPH-02622-5ug 5 µg - - -

7 - 10 business days*

99.00€
TGM-TMPH-02622-10ug 10 µg - - -

7 - 10 business days*

159.00€
TGM-TMPH-02622-50ug 50 µg - - -

7 - 10 business days*

404.00€
TGM-TMPH-02622-200ug 200 µg - - -

7 - 10 business days*

864.00€
TGM-TMPH-02622-500ug 500 µg - - -

7 - 10 business days*

1,535.00€
 
Description: Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase... more
Product information "DOCK8 Protein, Mouse, Recombinant (E. coli, His)"
Description: Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane. Is involved in NK cell cytotoxicity controlling polarization of microtubule-organizing center (MTOC), and possibly regulating CCDC88B-mediated lytic granule transport to MTOC during cell killing.
Keywords: Dock8 , Dedicator of cytokinesis protein 8
Supplier: TargetMol
Supplier-Nr: TMPH-02622

Properties

Conjugate: No
MW: 24.7 kD

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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