DOCK3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-10701.20	20 µg	-	-	-	10 - 15 business days*		90.00€
ABS-PP-10701.100	100 µg	-	-	-	10 - 15 business days*		180.00€

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Protein function: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some... more

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Product information "DOCK3 (human), recombinant protein"

Protein function: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of amyloid-beta APBA1 protein and lowers the rate of cell- substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors. [The UniProt Consortium]

Keywords:	Dedicator of cytokinesis protein 3, Modifier of cell adhesion, Presenilin-binding protein, PBP, Recombinant Human DOCK3 Protein
Supplier:	Absea
Supplier-Nr:	PP-10701

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	12 kD
Format:	Solution

Database Information

KEGG ID :	K05727 \| Matching products
UniProt ID :	Q8IZD9 \| Matching products
Gene ID :	GeneID 1795 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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