DNAJC3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-2159-L.20	20 µg		-	-	10 - 14 business days*		115.00€
ABS-PP-2159-L.100	100 µg		-	-	10 - 14 business days*		205.00€

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Protein function: Involved in the unfolded protein response (UPR) during endoplasmic reticulum... more

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Product information "DNAJC3 (human), recombinant protein"

Protein function: Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF- 2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity. [The UniProt Consortium]

Keywords:	DnaJ homolog subfamily C member 3, Endoplasmic reticulum DNA J domain-containing protein 6, ER-resident protein ERdj6, ERdj6, Interferon-induced, double-stranded RNA-activated protein kinase inhibitor, Protein kinase inhibitor of 58 kDa, Protein kinase in
Supplier:	Absea
Supplier-Nr:	PP-2159-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	44.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K09523 \| Matching products
UniProt ID :	Q13217 \| Matching products
Gene ID :	GeneID 5611 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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