DLL1/Delta1, His, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05223-100	100 µg		-		Request delivery time estimate		376.00€
GSC-Z05223-500	500 µg		-		Request delivery time estimate		1,263.00€

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DLL1, a Notch signaling ligand, is significantly overexpressed in ERalpha luminal breast cancer.... more

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Product information "DLL1/Delta1, His, Human"

DLL1, a Notch signaling ligand, is significantly overexpressed in ERalpha luminal breast cancer. Intriguingly, DLL1 overexpression correlates with poor prognosis in ERalpha luminal breast cancer, but not in other subtypes of breast cancer. In addition, this effect is specific to DLL1, as other Notch ligands (DLL3, JAGGED1, and JAGGED2) do not influence the clinical outcome of ERalpha patients. DLL1-mediated Notch signaling in breast cancer is important for tumor cell proliferation, angiogenesis, and cancer stem cell function.

Keywords:	DLL1, Delta-like protein 1, Drosophila Delta homolog 1
Supplier:	GenScript
Supplier-Nr:	Z05223

Properties

Conjugate:	No
Species reactivity:	human
MW:	57.6 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K06051 \| Matching products
UniProt ID :	O00548 \| Matching products
Gene ID :	GeneID 28514 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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