DEPDC5 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6341.20	20 µg		-	-	Request delivery time estimate		90.00€
ABS-PP-6341.100	100 µg		-	-	Request delivery time estimate		180.00€

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Protein function: As a component of the GATOR1 complex functions as an inhibitor of the amino... more

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Product information "DEPDC5 (human), recombinant protein"

Protein function: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway. [The UniProt Consortium]

Keywords:	GATOR1 complex protein DEPDC5, DEP domain-containing protein 5, Recombinant Human DEPDC5 Protein
Supplier:	Absea
Supplier-Nr:	PP-6341

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	35 kD
Format:	Solution

Database Information

KEGG ID :	K20404 \| Matching products
UniProt ID :	O75140 \| Matching products
Gene ID :	GeneID 9681 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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