DCUN1D1 Protein, Human, Recombinant (His)

DCUN1D1 Protein, Human, Recombinant (His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-TMPY-03869-100ug 100 µg -

5 - 10 business days*

658.00€
 
Description: DCUN1D1, also known as SCCRO, is part of an E3 ubiquitin ligase complex for... more
Product information "DCUN1D1 Protein, Human, Recombinant (His)"
Description: DCUN1D1, also known as SCCRO, is part of an E3 ubiquitin ligase complex for neddylation. DCUN1D1 functions to recruit charged E2 and is involved in the release of inhibitory effects of CAND1 on cullin-RING ligase E3 complex assembly and activity. DCUN1D1 binds to the components of the neddylation pathway (Cullin-ROC1, Ubc12, and CAND1) and augments but is not required for cullin neddylation in reactions using purified recombinant proteins. DCUN1D1 also recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation in purified protein assays. DCUN1D1 also acts as am ncogene facilitating malignant transformation and carcinogenic progression.
Keywords: Tes3, SCRO, RP42, DCUN1L1, DCN1, defective in cullin neddylation 1, domain containing 1, SCCRO, DCNL1
Supplier: TargetMol
Supplier-Nr: TMPY-03869

Properties

Conjugate: No
MW: 32 kD

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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