Cysteine-Rich with EGF-Like Domain Protein 2/CRELD2 Protein(C-6His) (recombinant human)

Protein Construction: Recombinant Human Cysteine-Rich with EGF-Like Domain Protein 2 is produced by our Mammalian expression system and the target gene encoding Ala25-Leu321 is expressed with a 6His tag at the C-terminus. Sequence: Ala25-Leu321. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 38 kDa. Protein function: Cysteine-Rich with EGF-Like Domain Protein 2 (CRELD2) is a secreted protein that is a member of the CRELD family. Human CRELD2 is synthesized as a 353 amino acid precursor protein with a signal peptide, a highly conserved domain rich in glutamic acid and tryptophan (WE) and EGF-like repeats. CRELD2 is ubiquitously expressed in many tissues. CRELD2 may interact with CHRNA4 and regulate transport of a4-ß2 neuronal acetylcholine receptor. In addition, CRELD2 could be a novel mediator in regulating the onset and progression of various ER stress-associated diseases. Protein function: May regulate transport of alpha4-beta2 neuronal acetylcholine receptor. [The UniProt Consortium]