Cynomolgus TNFR2/CD120b/TNFRSF1B Protein

Cynomolgus TNFR2/CD120b/TNFRSF1B Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
KT-TNF-CM1R2-100UG 100 µg -

7 - 10 business days*

269.00€
KT-TNF-CM1R2-500UG 500 µg -

7 - 10 business days*

898.00€
 
Recombinant Cynomolgus TNFR2/CD120b/TNFRSF1B Protein is expressed from HEK293 with His tag at the... more
Product information "Cynomolgus TNFR2/CD120b/TNFRSF1B Protein"
Recombinant Cynomolgus TNFR2/CD120b/TNFRSF1B Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu23-Asp257. Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Keywords: CD120b, Etanercept, p75TBPII, p75TNFR, TNF RII, TNF-R2, TNF-R75, TNFR80, TNFRSF1B, TNFR2, TBPII, TNFBR, TNFR1B
Supplier: KACTUS
Supplier-Nr: TNF-CM1R2

Properties

Host: Human cells
Species reactivity: Cynomolgus
MW: 26.1 kD
Purity: >95% (Tris-Bis PAGE),>95% (HPLC)
Format: Lyophilized

Database Information

UniProt ID : A0A2K5VEV7 | Matching products

Handling & Safety

Storage: -80°C (avoid repeat freezing and thawing cycles)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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