Cyclin-Dependant Kinase 4 (CDK-4) (Western Blot Control)

Protein Length: Met1- Glu303. Protein Tag: N terminal containing a HIS tag. Cyclin-dependent kinase 4 combines with the protein cyclin D to form a protein complex that promotes the passage of cells through the G1 checkpoint in the cell growth cycle. This cellular activity is regulated by the protein p16 produced by p16INK4a. Normally, p16 controls cell growth by inhibiting the activity of the CDK4-cyclin D complex and stopping cells at the G1 checkpoint. RANDOX recombinant CDK4 comprises a 303 amino acid fragment (1-303) corresponding to the mature CDK4 protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.