CXXC5 PrEST Antigen

CXXC5 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST89839.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: May indirectly participate in activation of the NF-kappa-B and MAPK pathways.... more
Product information "CXXC5 PrEST Antigen"
Protein function: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) (PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788). Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG (PubMed:29276034). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: CF5, RINF, CXXC5, HSPC195, CXXC-type zinc finger protein 5, Retinoid-inducible nuclear factor, Putative MAPK-activating protein PM08, Putative NF-kappa-B-activating protein 102
Supplier: Atlas Antibodies
Supplier-Nr: APrEST89839

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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