CRTAM, His, Mouse

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z06074-100	100 µg		-		7-10 business days*		403.00€
GSC-Z06074-500	500 µg		-		7-10 business days*		1,344.00€

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Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell... more

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Product information "CRTAM, His, Mouse"

Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNgamma by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile, therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.

Keywords:	Crtam, Cytotoxic and regulatory T-cell molecule, Class-I MHC-restricted T-cell-associated molecule
Supplier:	GenScript
Supplier-Nr:	Z06074

Properties

Conjugate:	No
Species reactivity:	mouse
MW:	31.1 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K16361 \| Matching products
UniProt ID :	Q149L7 \| Matching products
Gene ID :	GeneID 54698 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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