Complement component receptor 1-like protein (Cr1l), partial, recombinant rat

Organism: Rattus norvegicus (Rat). Source: E.coli. Expression Region: 36-482aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: GQCPAPPLFP YAKPINPTDE STFPVGTSLK YECRPGYIKR QFSITCEVNS VWTSPQDVCI RKQCETPLDP QNGIVHVNTD IRFGSSITYT CNEGYRLIGS SSAMCIISDQ SVAWDAEAPI CESIPCEIPP SIPNGDFFSP NREDFHYGMV VTYQCNTDAR GKKLFNLVGE PSIHCTSIDG QVGVWSGPPP QCIELNKCTP PHVENAVIVS KNKSLFSLRD MVEFRCQDGF MMKGDSSVYC RSLNRWEPQL PSCFKVKSCG AFLGELPNGH VFVPQNLQLG AKVTFVCNTG YQLKGNSSSH CVLDGVESIW NSSVPVCEQV ICKLPQDMSG FQKGLQMKKD YYYGDNVALE CEDGYTLEGS SQSQCQSDAS WDPPLPKCVS QVICKLPQDM SGFQKGLQMK KDYYYGDNVA LECEDGYTLE GSSQSQCQSD ASWDPPLPKC VSRSNSG. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. Relevance: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Seems to act as a costimulatory factor for T-cells. May play a crucial role in early embryonic development by maintaining fetomaternal tolerance. Reference: n/a. Function: nan