CLEC6A (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-11585.20	20 µg		-	-	Request delivery time estimate		90.00€
ABS-PP-11585.100	100 µg		-	-	Request delivery time estimate		180.00€

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Protein function: Binds high-mannose carbohydrates in a Ca(2+)-dependent manner... more

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Product information "CLEC6A (human), recombinant protein"

Protein function: Binds high-mannose carbohydrates in a Ca(2+)-dependent manner (PubMed:28652405). Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk- CARD9-NF-kappa-B-dependent pathway. [The UniProt Consortium]

Keywords:	C-type lectin domain family 6 member A, C-type lectin superfamily member 10, Dendritic cell-associated C-type lectin 2, DC-associated C-type lectin 2, Dectin-2, Recombinant Human CLEC6A Protein
Supplier:	Absea
Supplier-Nr:	PP-11585

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	31 kD
Format:	Solution

Database Information

KEGG ID :	K17514 \| Matching products
UniProt ID :	Q6EIG7 \| Matching products
Gene ID :	GeneID 93978 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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