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CILP (human), recombinant protein

Absea
CILP (human), recombinant protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-PP-034-L.20 20 µg - -

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115.00€
ABS-PP-034-L.100 100 µg - -

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205.00€
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You can also order by e-mail: info@biomol.com
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Description Product Citations Certificate of Analysis Reviews 0
Description
Protein function: Probably plays a role in cartilage scaffolding. May act by antagonizing... more
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Product information "CILP (human), recombinant protein"
Protein function: Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage. [The UniProt Consortium]
Keywords: Cartilage intermediate layer protein 1, CILP-1, Cartilage intermediate-layer protein) [Cleaved into: Cartilage intermediate layer protein 1 C1, Cartilage intermediate layer protein 1 C2], Recombinant Human CILP Protein
Supplier: Absea
Supplier-Nr: PP-034-L

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
MW: 11.5 kD
Format: Lyophilized

Database Information

KEGG ID : K24436 | Matching products
UniProt ID : O75339 | Matching products
Gene ID : GeneID 8483 | Matching products

Handling & Safety

Storage: -20°C (protect from light & moisture)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Product Citations
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