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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-RPCB0940.10 | 10 µg | - | - | - |
10 - 15 business days* |
145.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Endotoxin level: < 0.1 EU/µg of the protein by LAL method. Protein function: Cell surface... more
Product information "CEACAM5/CEA/CD66e Protein (recombinant human)"
Endotoxin level: < 0.1 EU/µg of the protein by LAL method. Protein function: Cell surface glycoprotein that plays a role in cell adhesion and tumor progression (PubMed:2803308, PubMed:2022629, PubMed:1378450, PubMed:8776764, PubMed:11590190, PubMed:10910050, PubMed:14724575, PubMed:16204051). Intercellular adhesion occurs in a calcium- and fibronectin-independent manner (PubMed:2022629, PubMed:16204051). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8 (PubMed:2803308, PubMed:2022629, PubMed:8776764, PubMed:11590190, PubMed:16204051). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764). Plays a role in neutrophil adhesion to cytokine-activated endothelial cells (PubMed:1378450). Plays a role as an oncogene by promoting tumor progression, positively regulates cell migration, cell adhesion to endothelial cells and cell invasion (PubMed:16204051). Also involved in the metastatic cascade process by inducing gain resistance to anoikis of pancreatic adenocarcinoma and colorectal carcinoma cells (PubMed:10910050, PubMed:14724575). [The UniProt Consortium]
| Keywords: | NCA, CD66c, CEACAM6, Normal cross-reacting antigen, Non-specific crossreacting antigen, Carcinoembryonic antigen-related cell adhesion molecule 6 |
| Supplier: | Assay Genie |
| Supplier-Nr: | RPCB0940 |
Properties
| Conjugate: | No |
| Host: | Human cells |
| Species reactivity: | human |
| Purity: | >95% (SDS-PAGE) |
Database Information
| KEGG ID : | K06499 | Matching products |
| UniProt ID : | P40199 | Matching products |
| Gene ID : | GeneID 4680 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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