CDKN1B (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-581-L.20	20 µg		-	-	10 - 15 business days*		115.00€
ABS-PP-581-L.100	100 µg		-	-	10 - 15 business days*		205.00€

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Protein function: Important regulator of cell cycle progression. Inhibits the kinase activity of... more

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Product information "CDKN1B (human), recombinant protein"

Protein function: Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA (PubMed:28666995). Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. [The UniProt Consortium]

Keywords:	Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, Recombinant Human CDKN1B Protein
Supplier:	Absea
Supplier-Nr:	PP-581-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	13.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K06624 \| Matching products
UniProt ID :	P46527 \| Matching products
Gene ID :	GeneID 1027 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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