CDK5RAP1 PrEST Antigen

CDK5RAP1 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST90170.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Methylthiotransferase that catalyzes the conversion of N6-... more
Product information "CDK5RAP1 PrEST Antigen"
Protein function: Methylthiotransferase that catalyzes the conversion of N6- (dimethylallyl)adenosine (i(6)A) to 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 (adjacent to the 3'-end of the anticodon) of four mitochondrial DNA-encoded tRNAs (Ser(UCN), Phe, Tyr and Trp) (PubMed:22422838, PubMed:25738458, PubMed:28981754). Essential for efficient and highly accurate protein translation by the ribosome (PubMed:22422838, PubMed:25738458, PubMed:28981754). Specifically inhibits CDK5 activation by CDK5R1 (PubMed:11882646). Essential for efficient mitochondrial protein synthesis and respiratory chain, shows pathological consequences in mitochondrial disease (PubMed:25738458). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: CGI-05, C20orf34, CDK5 activator-binding protein C42, CDK5 regulatory subunit-associated protein 1, Mitochondrial tRNA methylthiotransferase CDK5RAP1, mt-tRNA-2-methylthio-N6-dimethylallyladenosine synthase
Supplier: Atlas Antibodies
Supplier-Nr: APrEST90170

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Database Information

UniProt ID : Q96SZ6 | Matching products
Gene ID : GeneID 51654 | Matching products

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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