CDK5R1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-10573-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-10573-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required... more

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Product information "CDK5R1 (human), recombinant protein"

Protein function: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution. [The UniProt Consortium]

Keywords:	Cyclin-dependent kinase 5 activator 1, CDK5 activator 1, Cyclin-dependent kinase 5 regulatory subunit 1, TPKII regulatory subunit) [Cleaved into: Cyclin-dependent kinase 5 activator 1, p35, p35, Cyclin-dependent kinase 5 activator 1, p25, p25, Tau protein
Supplier:	Absea
Supplier-Nr:	PP-10573-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	53.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K11716 \| Matching products
UniProt ID :	Q15078 \| Matching products
Gene ID :	GeneID 8851 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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