CDC42BPB PrEST Antigen

CDC42BPB PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST70503.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Serine/threonine-protein kinase which is an important downstream effector of... more
Product information "CDC42BPB PrEST Antigen"
Protein function: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715, PubMed:21949762). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates PPP1R12A (PubMed:21457715). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: MRCK beta, EC=2.7.11.1, CDC42BP-beta, DMPK-like beta, CDC42-binding protein kinase beta, Serine/threonine-protein kinase MRCK beta, Myotonic dystrophy protein kinase-like beta
Supplier: Atlas Antibodies
Supplier-Nr: APrEST70503

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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