CDC42BPB (human), recombinant protein

CDC42BPB (human), recombinant protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-PP-5597-L.20 20 µg - -

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115.00€
ABS-PP-5597-L.100 100 µg - -

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205.00€
 
Protein function: Serine/threonine-protein kinase which is an important downstream effector of... more
Product information "CDC42BPB (human), recombinant protein"
Protein function: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715, PubMed:21949762). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates PPP1R12A (PubMed:21457715). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. [The UniProt Consortium]
Keywords: Serine/threonine-protein kinase MRCK beta, CDC42-binding protein kinase beta, CDC42BP-beta, DMPK-like beta, Myotonic dystrophy kinase-related CDC42-binding kinase beta, MRCK beta, Myotonic dystrophy protein kinase-like beta, Recombinant Human CDC42BPB Pro
Supplier: Absea
Supplier-Nr: PP-5597-L

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
MW: 41.5 kD
Format: Lyophilized

Handling & Safety

Storage: -20°C (protect from light & moisture)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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