CDC14B PrEST Antigen

CDC14B PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST94261.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Dual-specificity phosphatase involved in DNA damage response. Essential... more
Product information "CDC14B PrEST Antigen"
Protein function: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: CDC14B, EC=3.1.3.48, EC=3.1.3.16, CDC14 cell division cycle 14 homolog B, Dual specificity protein phosphatase CDC14B
Supplier: Atlas Antibodies
Supplier-Nr: APrEST94261

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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