CDC14B (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-10191.20	20 µg	-	-	-	Request delivery time estimate		90.00€
ABS-PP-10191.100	100 µg	-	-	-	Request delivery time estimate		180.00€

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Protein function: Dual-specificity phosphatase involved in DNA damage response. Essential... more

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Product information "CDC14B (human), recombinant protein"

Protein function: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases. [The UniProt Consortium]

Keywords:	Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, Recombinant Human CDC14B Protein
Supplier:	Absea
Supplier-Nr:	PP-10191

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	12.5 kD
Format:	Solution

Database Information

KEGG ID :	K06639 \| Matching products
UniProt ID :	O60729 \| Matching products
Gene ID :	GeneID 8555 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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